SLE is a world leader in the design and manufacture of neonatal ventilators. Years of ventilation experience have given the company an understanding of the challenges facing clinicians when caring for the tiniest and most critical babies. From being pioneers of neonatal Patient Triggered Ventilation (PTV) in the 1980’s, to the introduction of combined HFO (High Frequency Oscillation) in the 1990’s, SLE has maintained a position of leadership in neonatal ventilation. The company’s guiding principle is to support clinical and nursing staff in their everyday work. SLE has developed close relationships with leading universities, hospitals and other specialists and has created a ventilator that meets the highest standards using innovative solutions to clinical challenges. The knowledge and experience gained during years of development is evident in the SLE5000 ventilator: the result of SLE’s ongoing commitments to innovation, competency and care.

Modes Include:

• CPAP, CMV+ TTV, PTV, PSV, SIMV+ TTV + PSV, HFO, HFO+CMV
• Ability to preset parameters in all modes of operation 
• Powerful HFO with active expiration to cover a wide range of patients 
• Full colour, total touch-screen operation 
• Integral flow monitoring measuring lung mechanics and displaying of loops and waveforms 
• Trending of measured parameters 
• Standard patient circuit for all modes including HFO (except with NO therapy) 
• Unique, patented valveless technology 
• Integral battery with up to 60 minutes operating capability 
• Software based, allowing for upgrading to versions with new or improved functions

Targeted Tidal Volume (TTV):

• There is increasing clinical evidence to suggest that it is volutrauma that causes lung injury, which is worsened by barotrauma. It is also evident that efficient gaseous exchange is dependant on the delivery of appropriate tidal volumes. 
• Targeted Tidal Volume enables the user to select a target volume that they wish to achieve, allowing the ventilator to adjust PIP and Ti to achieve and maintain the selected tidal volume.

Main benefits of TTV:

• Reduction in volutrauma 
• A stable tidal volume accommodating changes in resistance and compliance 
• A more stable PaCO2 ,at the lowest possible pressure resulting in reduced episodes of hypocapnia and hypercapnia 
• Reduction in barotrauma 
• Ability to self wean

Pressure Support Ventilation (PSV):

• In this mode of ventilation the infant has the ability to trigger and terminate every breath. The main aim of PSV is to reduce the ‘work of breathing’ (WOB) in the spontaneously breathing infant.

Main benefits of PSV:

• Reduced WOB 
• Improved infant/ventilator synchrony 
• Reduced need for sedation 
• Retraining of respiratory musculature 
• Reduced time to wean
• PSV is designed and used in the weaning process and can be used with or without Synchronous Intermittent Mandatory Ventilation (SIMV).

High Frequency Oscillation (HFO):

• In the SLE5000, HFO is powerful enough to cater for a wide range of patients, dependant on lung mechanics. The SLE5000 provides sinusoidal ventilation with active expiration.

Main benefits of HFO:

• Improves ventilation at lower pressures 
• Higher levels of PEEP can be used without having to use high peak airway pressures to maintain appropriate levels of CO2 
• Produces more uniform lung recruitment 
• Reduces airleaks 
• Improved oxygenation in infants with severe RDS